Treatment of Nonvariceal Upper Gastrointestinal Bleeding

Acid-suppressive therapy is beneficial in the brass of UGB.
It reduces the rate of rebleeding, the need for OR, action requirements, and the extent of infirmary stay.
To date, no pharmacologic locating has demonstrated a chemical reaction in the fatality rate rates of patients with UGB.
An optimal acid-suppressive regimen has not yet been clearly established.

Since the subject matter and assent of this publisher, a thoughtfulness by Hsu et al. was published comparing i.v. pantoprazole (40 mg pill dose followed by 40 mg every 12 hours) with i.v. ranitidine (50 mg ball dose followed by 50 mg every 8 hours) in 102 patients who had received prior endoscopic idiom.
Of the 52 patients receiving pantoprazole, bleeding recurred in just 2 patients (4%), compared with 8 (16%) of those in the ranitidine unit ( n = 50) ( p = 0.04).
Also, i.v. esomeprazole (Nexium, AstraZeneca) and lansoprazole (Prevacid, TAP Pharmaceutical Products) have become available in the United States.
This is a part of article Treatment of Nonvariceal Upper Gastrointestinal Bleeding Taken from "Nexium Generic Esomeprazole" Information Blog